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Senior Manager - Finance

Axsome Therapeutics · New York City · United States

Remote USD 130k–150k / year Posted Open until 19 Oct 2026
  • Remote We are unable to consider candidates who are looking for fully remote roles. — job description

The job, in the employer's words

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X. 

About This Role 

Axsome Therapeutics is seeking a Senior Manager, Finance who will be responsible for the preparation of Axsome's external financial reporting, including its periodic SEC filings, the research and documentation of technical accounting matters affecting the Company's financial statements, supporting the design, improvement, and testing of internal controls under SOX 404 for areas under responsibility. The Senior Manager, Finance will play a central role in the quarterly and annual external reporting cycle, working with colleagues in finance and throughout the organization in the preparation of financial statements, including drafting, reviewing, and improving the quality of information provided to readers and stakeholders. The Senior Manager, Finance will be a trusted business partner across finance, legal, investor relations, and Axsome's internal and external audit partners. This role will report directly to the Senior Director, Finance. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following: 

  • Prepare Axsome's external financial statements and footnotes, including the statement of cash flows, along with the Management's Discussion and Analysis, supporting schedules for the Forms 10-Q and 10-K, and XBRL review 
  • Research and draft technical accounting memoranda on non-routine transactions, including share-based compensation awards, debt and equity instruments, business combinations, asset acquisitions, in- and out-licensing arrangements, and collaboration arrangements 
  • Monitor new accounting pronouncements and SEC rulemaking, assess applicability to Axsome, and prepare documentation and lead implementation 
  • Support the design, improvement, and testing of internal controls under SOX 404 for areas under responsibility, including control documentation and coordination with the Company’s internal audit service provider and external auditor 
  • Draft new accounting policies and periodically review and update existing policies 

Requirements / Qualifications 

  • Bachelor's or Master's degree in Accounting, Finance, or a related field; CPA required 
  • 7+ years of progressive accounting experience, ideally a mix of public accounting and SEC reporting/technical accounting 
  • Strong working knowledge of U.S. GAAP and SEC reporting requirements 
  • Experience with SOX 404 compliance at a public company, including the design, documentation, and testing of business process controls 
  • Experience with financial reporting tools such as DFIN Active Disclosure or Workiva preferred 
  • Experience in biopharmaceutical or life sciences industry preferred 
  • Ability to work on site Monday, Tuesday, and Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience, Knowledge and Skills 

  • Strong technical accounting research skills, with the ability to analyze authoritative guidance and reach and document supportable conclusions 
  • Excellent oral and written communication skills, with the ability to draft clear technical accounting documentation and articulate conclusions to non-technical audiences 
  • Demonstrated ability to manage multiple deliverables against fixed external filing deadlines 
  • Possess a problem-solving mindset with demonstrated "lean-forward" approach and the ability to think critically 
  • Proficiency with accounting research tools such as Intelligize, Checkpoint, or FASB codifications 
  • Experience with ERP and financial close systems, such as Microsoft Dynamics 365 Business Central 
  • Strong planning and organizational skills, attention to detail, execution, and follow-through 

Salary & Benefits

The anticipated salary range for this role is $130,000 - $150,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Benefits mentioned

  • The anticipated salary range for this role is $130,000 - $150,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
  • Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
  • Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Requirements mentioned

  • Bachelor's or Master's degree in Accounting, Finance, or a related field; CPA required
  • 7+ years of progressive accounting experience, ideally a mix of public accounting and SEC reporting/technical accounting
  • Strong working knowledge of U.S. GAAP and SEC reporting requirements
  • Experience with SOX 404 compliance at a public company, including the design, documentation, and testing of business process controls
  • Experience with financial reporting tools such as DFIN Active Disclosure or Workiva preferred
  • Experience in biopharmaceutical or life sciences industry preferred
  • Ability to work on site Monday, Tuesday, and Thursday. We are unable to consider candidates who are looking for fully remote roles
  • Strong technical accounting research skills, with the ability to analyze authoritative guidance and reach and document supportable conclusions
  • Excellent oral and written communication skills, with the ability to draft clear technical accounting documentation and articulate conclusions to non-technical audiences
  • Demonstrated ability to manage multiple deliverables against fixed external filing deadlines
  • Possess a problem-solving mindset with demonstrated "lean-forward" approach and the ability to think critically
  • Proficiency with accounting research tools such as Intelligize, Checkpoint, or FASB codifications
  • Experience with ERP and financial close systems, such as Microsoft Dynamics 365 Business Central
  • Strong planning and organizational skills, attention to detail, execution, and follow-through

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