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Senior Director - Avexitide Brand Lead

Amylyx Pharmaceuticals · Cambridge · United States

Remote USD 277k–312k / year Posted Open until 18 Oct 2026
  • Remote At Amylyx, we proudly support remote work opportunities within the United States. — job description

The job, in the employer's words

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

Amylyx Pharmaceuticals is seeking a Senior Director, Avexitide Brand Lead to provide strategic leadership for the potential launch and commercialization of avexitide and serve as the enterprise marketing leader responsible for brand strategy and long-term brand growth. This role will develop and execute the integrated marketing strategy for avexitide, for post-bariatric hypoglycemia (PBH), while establishing the foundation for future indications. The Senior Director will partner closely within Marketing and across Sales, Market Access, Commercial Operations, Medical Affairs, Regulatory, Corporate Communications, and Advocacy to ensure successful commercialization and long-term brand success.

Responsibilities

  • Own the enterprise-wide brand strategy for avexitide from launch planning, through commercialization and future indication planning.
  • Serve as a key stakeholder in establishing and achieving marketing KPIs
  • Lead development and execution of insight-driven marketing plan, including targeting & segmentation, value proposition, competitive strategy, positioning, core messaging, and annual brand planning.
  • Lead the HCP marketing team in developing integrated healthcare provider marketing plans for endocrinologists, bariatric surgeons, and other relevant stakeholders.
  • Lead community marketing team in developing patient and caregiver engagement strategies, including patient activation initiatives, and collaborate with Advocacy and Patient Services to optimize the patient journey and support programs.
  • Deliver disease state and promotional campaigns, educational initiatives, field engagement tools, CRM journey, digital assets, and other tactics that support promotional and omnichannel objectives.
  • Partner with Medical Affairs, Advocacy, and Corporate Communications to support a consistent engagement experience for healthcare providers, patients, caregivers, and advocacy organizations.
  • Ensure that the brand strategic perspective is represented in market research, commercial forecast, long-range business planning, pricing, access, trade, and other key commercial decisions and workstreams. Align with Medical for evidence-generation and data-dissemination strategies.
  • Oversee the avexitide brand marketing budget.
  • Build, develop, and lead a high-performing brand team and manage external partners toward accountability, collaboration, innovation, and long-term product success.

Required Qualifications

  • Bachelor’s degree in Marketing, Business, Life Sciences, or a related field required; advanced degree such as an MBA, MPH, or equivalent preferred.
  • Minimum of 15 years of progressive pharmaceutical, biotechnology, or healthcare marketing experience with demonstrated success in brand management and commercial launch strategy.
  • Demonstrated brand leadership resulting in successful product launches in biotechnology or specialty pharmaceuticals.
  • Demonstrated success developing integrated healthcare provider, patient, caregiver, and disease awareness marketing strategies.
  • Experience managing significant commercial budgets and external agency partnerships.
  • Experience leading and working cross-functional commercial teams and influencing executive leadership on enterprise-wide strategic decisions. Demonstrated contributions as a member of program and lifecycle teams, integrated evidence generation planning group, pricing committees, and other strategic cross-functional bodies.
  • Exceptional strategic thinking, analytical, leadership, problem-solving, executive communication, presentation, and relationship-building skills.
  • Proven ability to build, develop, and lead high-performing teams in a fast-paced, evolving commercial environment.

Preferred Requirements

  • Rare disease, endocrinology, metabolic disease, or specialty pharmaceutical experience strongly preferred.
  • Experience commercializing products for high unmet-need patient communities and/or first-to-market therapies for rare therapeutic categories preferred.
  • Experience building scalable brand, market development, and patient engagement capabilities in a growing organization preferred.

Work Location and Conditions

  • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
  • You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
  • You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Compensation

The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.

Estimated Pay Range
$277,000—$312,000 USD

To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn.

To return to our website please click here.

Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Benefits mentioned

  • The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.
  • Estimated Pay Range
  • $277,000—$312,000 USD

Requirements mentioned

  • Bachelor’s degree in Marketing, Business, Life Sciences, or a related field required; advanced degree such as an MBA, MPH, or equivalent preferred.
  • Minimum of 15 years of progressive pharmaceutical, biotechnology, or healthcare marketing experience with demonstrated success in brand management and commercial launch strategy.
  • Demonstrated brand leadership resulting in successful product launches in biotechnology or specialty pharmaceuticals.
  • Demonstrated success developing integrated healthcare provider, patient, caregiver, and disease awareness marketing strategies.
  • Experience managing significant commercial budgets and external agency partnerships.
  • Experience leading and working cross-functional commercial teams and influencing executive leadership on enterprise-wide strategic decisions. Demonstrated contributions as a member of program and lifecycle teams, integrated evidence generation planning group, pricing committees, and other strategic cross-functional bodies.
  • Exceptional strategic thinking, analytical, leadership, problem-solving, executive communication, presentation, and relationship-building skills.
  • Proven ability to build, develop, and lead high-performing teams in a fast-paced, evolving commercial environment.
  • Rare disease, endocrinology, metabolic disease, or specialty pharmaceutical experience strongly preferred.
  • Experience commercializing products for high unmet-need patient communities and/or first-to-market therapies for rare therapeutic categories preferred.
  • Experience building scalable brand, market development, and patient engagement capabilities in a growing organization preferred.

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