← All jobs in United States

Remote

Enterprise Systems Lead

General Matter · Los Angeles · United States

Remote USD 185k–245k / year Posted Open until 19 Oct 2026
  • Remote Hybrid and remote work will not be considered. — job description

The job, in the employer's words

About the Company

General Matter is enriching uranium in America. 

Our goal is to design, build, and operate the world’s lowest-cost enrichment services in the United States.  

Our mission is to restore America’s ability to produce nuclear fuel—fuel that will power AI, advanced manufacturing, critical industries, and the next generation of nuclear reactors. 

Ultimately, our work will help power national ambitions and enable a high-energy society. 

We were incubated by Founders Fund, like Anduril and Palantir before us, and are backed by top-tier investors. Our lean, world-class team of engineers and operators is applying a first-principles approach to solving the problem of nuclear fuel production.  

We are a mission-driven company with a culture of urgency, accountability, and transparency. 

Help us build a high-energy society by making the cleanest, safest form of baseload energy the most affordable. 

About This Role

You will own the business systems that run General Matter: the ERP and the manufacturing, quality, engineering, supply chain, and finance platforms around it, plus the integrations and the data that connect them. This is the business-systems layer, distinct from the enterprise technology and IT infrastructure it runs on. Reporting to the VP of Software, you will own the systems strategy and the multi-year roadmap, carry platform selection including the ERP, and build the team that delivers it. 

This is a build role. We are standing up these systems for the first time, in a regulated environment and against a licensing calendar, so the work runs from selection through implementation and into operation. You will work across every department that depends on these platforms, and escalate the decisions that need your manager or above with clear options and a recommendation. 

Key Stakeholders: Manufacturing, Engineering, Quality, Supply Chain and Procurement, Finance and Accounting, IT, Security, HR and People, Legal and Compliance, and Executive Leadership. 

Responsibilities:

  • Own the enterprise systems strategy and the multi-year roadmap across the portfolio (ERP, MES, QMS, WMS, CRM, HRIS, PLM/PDM, procurement, finance, and project controls), and hold the requirements and priorities for each major system until it has a product owner. 
  • Lead platform selection with the program manager and architect, running requirements, vendor evaluation, and fit-gap analysis against the compliance gates, negotiating commercial terms, and carrying the recommendation to leadership for decision. 
  • Set the data governance rules across the portfolio, including the system-of-record decision for each data domain and the data-quality baseline that gates migration. 
  • Decide where each system and data set is hosted across environments of differing data sensitivity, and how data crosses between controlled and uncontrolled environments, designing to the determinations Legal and Export Control make. 
  • Build and lead the team, defining the roles, hiring and onboarding across product, program management, engineering, analysis, and administration, and setting the technical and documentation standards they work to. 
  • Deliver the systems the license basis depends on, with Quality, Regulatory, and Configuration Management, including the QMS build and the document-control, records, and configuration-baseline capabilities. 
  • Report portfolio status, risk, and options to your manager and the stakeholder departments on a regular cadence, and own the enterprise-systems mitigation tasks on the company risk register. 
  • Lead the build of the interim systems and internal tooling the business needs before a commercial platform covers the capability, setting the requirements and the technical direction and keeping them running until it does. 

Basic Qualifications:

  • 10+ years in enterprise or business systems, including ownership of a multi-system portfolio and a leadership role on at least one full-cycle ERP or enterprise-platform implementation. 
  • Experience owning platform selection end to end, from requirements and vendor evaluation through commercial terms and the implementation-partner or systems-integrator engagement. 
  • Experience building and leading a team, including defining roles, hiring, and setting technical and documentation standards. 
  • Technical fluency across enterprise platforms such as ERP, MES, QMS, PLM/PDM, WMS, HRIS, and procurement, and their integrations, sufficient to lead technical decisions with architects and engineers. 
  • Strong understanding of the business processes these systems serve, across manufacturing, supply chain and procurement, quality, engineering data, and finance. 
  • Experience with data governance and master data management across a multi-system landscape, including system-of-record design. 
  • Experience operating in a regulated environment, including access control, auditable change management, and data-handling constraints such as export control. 
  • Experience bringing a portfolio decision to executive leadership as a clear recommendation. 
  • Bachelor's degree in Information Systems, Computer Science, Engineering, or a related field, or equivalent experience. 

Preferred Skills and Experience:

  • Hands-on technical depth, including the ability to read and write code, work directly against platform APIs, and prototype where it unblocks a decision. 
  • Experience standing up a systems landscape for the first time, rather than optimizing an established ERP. 
  • Experience in regulated industries such as nuclear, aerospace, defense, energy, or medical device, and familiarity with frameworks such as NQA-1, ISO 9001, AS9100, 21 CFR Part 11, SOC 2, or ISO 27001. 
  • Familiarity with US export control, such as 10 CFR Part 810 or the EAR, and with government-cloud hosting such as AWS GovCloud or FedRAMP-authorized platforms. 
  • Experience with platforms such as Oracle Fusion, SAP, NetSuite, or Microsoft Dynamics, a commercial MES, a commercial QMS, and SolidWorks PDM or a comparable PLM. 
  • Experience managing consultants, systems integrators, and software contracts against scope and budget. 

Additional Requirements

  • Ability to work extended hours and weekends as necessary.
  • Based in Los Angeles, CA, and onsite full-time. Hybrid and remote work will not be considered. 

Equal Opportunity Employer

General Matter is an Equal Opportunity Employer; employment with General Matter is governed on the basis of merit, competence and qualifications and will not be influenced in any manner by race, color, religion, gender, national origin/ethnicity, veteran status, disability status, age, sexual orientation, gender identity, marital status, mental or physical disability or any other legally protected status.

Compensation and Benefits

The base salary range for this role is $185,000-$245,000 annually. 

Compensation bands are determined by role, level, location, and alignment with market data. Individual level and base pay is determined on a case-by-case basis and may vary based on job-related skills, education, experience, technical capabilities and internal equity. Please note that the stated salary range is an estimate and may be adjusted based on market conditions, business needs, or other factors. In addition to base salary, for full-time hires, you may also be eligible for long-term incentives, in the form of stock options, and access to medical, vision & dental coverage as well as access to a 401(k) retirement plan.

Benefits mentioned

  • The base salary range for this role is $185,000-$245,000 annually.

Requirements mentioned

  • 10+ years in enterprise or business systems, including ownership of a multi-system portfolio and a leadership role on at least one full-cycle ERP or enterprise-platform implementation.
  • Experience owning platform selection end to end, from requirements and vendor evaluation through commercial terms and the implementation-partner or systems-integrator engagement.
  • Experience building and leading a team, including defining roles, hiring, and setting technical and documentation standards.
  • Technical fluency across enterprise platforms such as ERP, MES, QMS, PLM/PDM, WMS, HRIS, and procurement, and their integrations, sufficient to lead technical decisions with architects and engineers.
  • Strong understanding of the business processes these systems serve, across manufacturing, supply chain and procurement, quality, engineering data, and finance.
  • Experience with data governance and master data management across a multi-system landscape, including system-of-record design.
  • Experience operating in a regulated environment, including access control, auditable change management, and data-handling constraints such as export control.
  • Experience bringing a portfolio decision to executive leadership as a clear recommendation.
  • Bachelor's degree in Information Systems, Computer Science, Engineering, or a related field, or equivalent experience.
  • Hands-on technical depth, including the ability to read and write code, work directly against platform APIs, and prototype where it unblocks a decision.
  • Experience standing up a systems landscape for the first time, rather than optimizing an established ERP.
  • Experience in regulated industries such as nuclear, aerospace, defense, energy, or medical device, and familiarity with frameworks such as NQA-1, ISO 9001, AS9100, 21 CFR Part 11, SOC 2, or ISO 27001.
  • Familiarity with US export control, such as 10 CFR Part 810 or the EAR, and with government-cloud hosting such as AWS GovCloud or FedRAMP-authorized platforms.
  • Experience with platforms such as Oracle Fusion, SAP, NetSuite, or Microsoft Dynamics, a commercial MES, a commercial QMS, and SolidWorks PDM or a comparable PLM.
  • Experience managing consultants, systems integrators, and software contracts against scope and budget.
  • Ability to work extended hours and weekends as necessary.
  • Based in Los Angeles, CA, and onsite full-time. Hybrid and remote work will not be considered.

No Mondays shows this listing as the employer published it. Check the details on the employer's site before you apply.

More remote jobs in United States

Natera · US Remote · today

Medical Science Liaison - Rare Disease

POSITION SUMMARY: The Medical Science Liaison (MSL), Rare Disease is a field-based scientific expert and a key scientific resource for clinicians, academic institutions, …

RemoteUSD 131k–163k / year
Vercel · San Francisco · today

GTM Engineer

About Vercel: Vercel is the agentic infrastructure company, freeing people and agents to ship what's next. For more than a decade we've helped builders move from idea to …

RemoteUSD 180k–295k / year
Cortica - Neurodevelopmental · San Diego · today

Enrollment Specialist - Remote

Cortica is looking for an Enrollment Specialist to join our growing multi-disciplinary team! Under the general direction of the Cortica Head of Client Experience, the Enr…

RemoteUSD 23–25 / hour
Sayari · Remote - US · today

Field Intelligence Analyst - US

About Sayari: Sayari is the judgment infrastructure for trustworthy AI in economic security and commercial risk. The Sayari Commercial World Model resolves 11.7B+ primary…

Remote
Symmetry AI · Denver · today

Forward Deployed Solution Engineer

Symmetry is the payroll infrastructure for software & payroll platforms powering the paychecks of over 64 million workers each year. Our fully integrated suite of payroll…

Remote
Wiz, Inc. · Remote - USA · today

Head of Strategic Programs Operations

Come join the organization that is redefining security for the AI era. As one of the fastest-growing startups ever, we enable teams to secure cloud and AI applications by…

RemoteUSD 234k–300k / year

23,426 live roles · See all →

Other roles at General Matter

General Matter · Los Angeles · 13 days ago

Technical Recruiter - Hardware Engineering

About the Company: General Matter enriches uranium. We are designing, building, and operating the world's lowest-cost enrichment services, here in the US. In the process,…

RemoteUSD 100k–180k / year
General Matter · Los Angeles · 44 days ago

Summer 2027 Internship - Business Development

About the company General Matter enriches uranium. We are designing, building, and operating the world’s lowest-cost enrichment services, here in the US. In the process, …

RemoteUSD 28–36 / hour
General Matter · Paducah · 44 days ago

IT Manager

About the Company At General Matter, we’re strengthening America’s capacity in nuclear energy to create a new set of possibilities, from generating clean energy at scale …

Unlimited leaveUSD 100k–160k / year
General Matter · Los Angeles · 2 months ago

Business & Operations Recruiter

About the Company: General Matter enriches uranium. We are designing, building, and operating the world’s lowest-cost enrichment services, here in the US. In the process,…

RemoteUSD 100k–200k / year
General Matter · Los Angeles · 2 months ago

Management Associate

About the Company General Matter is enriching uranium in America. Our mission is to restore our country’s ability to make nuclear fuel. Our fuel will help power AI, manuf…

RemoteUSD 80k–140k / year
General Matter · Los Angeles · 3 months ago

Campus Engagement & Early Talent Recruiter

About the Company General Matter enriches uranium. We are designing, building, and operating the world’s lowest-cost enrichment services, here in the US. In the process, …

RemoteUSD 90k–160k / year

11 live roles · See all →