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Director - Compensation - Benefits and HR Systems

Iambic Therapeutics, Inc · San Diego · United States

Remote Full time Posted Open until 18 Oct 2026

The job, in the employer's words

JOB SUMMARY

We are hiring a Director of Compensation, Benefits and HR Systems to join our growing Human Resources team at Iambic Therapeutic's. Reporting to the Head of HR, this role will lead the design, implementation and ongoing management of Iambic’s compensation, benefits and HR technology platforms. They will ensure our programs are competitive, scalable, compliant, and aligned with Iambic’s talent strategy and business objectives, supporting a rapidly growing biotech company. This role is based at our San Diego Headquarters.

KEY RESPONSIBILITIES

  • Lead the company’s compensation strategy and programs, including salary structures, job leveling, annual compensation reviews, bonus programs, equity guidelines, promotions, and market benchmarking.

  • Manage executive, employee and international compensation benchmarking

  • Oversee employee benefits programs, including health insurance, retirement, leave, wellness, and other benefit offerings; evaluate competitiveness, cost, and employee experience.

  • Lead annual benefits renewal and open enrollment processes and manage relationships with brokers, consultants, and benefit vendors.

  • Own HRIS strategy and administration, including PEO exit, ensuring systems, workflows, integrations, reporting, and data are accurate, efficient, and scalable.

  • Establish and maintain policies, controls, documentation, and governance across compensation, benefits, and HR systems.

  • Identify opportunities to automate and streamline HR processes and improve the employee and manager experience.

  • Stay current on market trends, regulatory requirements, and emerging practices in compensation, benefits, and HR technology.

QUALIFICATIONS

  • Bachelor’s degree in human resources, business administration, finance or related field, Certified Compensation Professional (CCP) preferred.

  • 12+ years of progressive HR experience with significant expertise in compensation, benefits, and/or HRIS, including experience leading total rewards programs.

  • Strong knowledge of compensation benchmarking, salary structures, incentive compensation, equity programs, and job architecture. International experience a plus

  • Experience managing U.S. benefits programs and working with brokers, consultants, and vendors.

  • Demonstrated HRIS expertise, including system implementation, optimization, reporting, and data governance.

  • Strong analytical skills with the ability to translate complex compensation and workforce data into actionable recommendations.

  • Experience partnering with senior executives, Finance, Legal, and HR leadership.

  • Strong project management skills and ability to manage multiple priorities in a fast-paced environment.

  • Experience with a successful transition off a PEO, standing up in-house payroll, benefits administration, and HR Systems preferred.

  • Experience in a high-growth, biotechnology, technology, or public-company environment preferred.

ABOUT IAMBIC THERAPEUTICS

Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai.

MISSION & CORE VALUES

Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

PAY AND BENEFITS

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

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